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Interleukin-1 alpha Mouse ELISA

  • Regulatory status:RUO
  • Type:Sandwich ELISA, Biotin-labelled antibody
  • Other names:Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF), Interleukin-1α
  • Species:Mouse
Cat. No. Size Price


RAF046R 96 wells (1 kit) $694,28
PubMed Product Details
Technical Data

Type

Sandwich ELISA, Biotin-labelled antibody

Applications

Serum, Cell culture supernatant

Sample Requirements

50 µl/well

Shipping

At ambient temperature. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Curve

Calibration Range

7.8–500 pg/ml

Limit of Detection

4 pg/ml

Intra-assay (Within-Run)

CV = 5.0%

Inter-assay (Run-to-Run)

CV = 10.0%

Spiking Recovery

75,00%

Dilution Linearity

101,00%

Summary

Research topic

Cytokines and chemokines and related molecules, Diabetology - Other Relevant Products, Immune Response, Infection and Inflammation, Neural tissue markers, Oncology, Transplantation, Animal studies

Summary

IL-1α is predominantly a cell-associated, non-secreted proinflammatory cytokine. It is produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. High levels of IL-1α are associated with sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, and atherosclerosis.

Product References (1)

References

  • Aoki M, Murase T. Obesity-associated insulin resistance adversely affects skin function. PLoS One. 2019 Oct 3;14(10):e0223528. doi: 10.1371/journal.pone.0223528. eCollection 2019. PubMed PMID: 31581253. PubMed CentralPMCID: PMC6776356. See more on PubMed
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