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Prostaglandin E2 StressXpress® ELISA

  • Regulatory status:RUO
  • Type:Competitive ELISA
  • Species:Multispecies
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Cat. No. Size Price


RSKT-207R 96 wells (1 kit)
PubMed Product Details
Technical Data

Type

Competitive ELISA

Applications

Serum, Plasma-EDTA, Plasma-Heparin, Urine, Cell lysate, Saliva, Tissue culture medium

Storage/Expiration

Store the complete kit at –20°C. Under these conditions, the kit is stable until the expiration date (see label on the box). Shipping at 2–8°C.

Calibration Range

1.953–500 pg/ml

Limit of Detection

3.25 pg/mL

Summary

Features

  • ELISA kit used to quantitate PGE2 in serum, plasma, urine, saliva and culture media samples
  • The total assay time is less than 3 hours

Research topic

Others, Animal studies

Summary

Prostaglandins are synthesized by cyclooxygenase enzymes, which initially convert arachidonic acid to Prostaglandin H2. Prostaglandin synthases then converts Prostaglandin H2 to Prostaglandin E2 (PGE2). This prostaglandin is a vasodilator, as well as facilitator of modulation of sleep/wake cycles, and human immunodeficiency virus replication. PGE2 is associated with several disease states including inflammation, arthritis, endometriosis, and a variety of cancers.

Summary References (3)

References to Prostaglandin E2

  • Hayaishi O. Sleep-wake regulation by prostaglandins D2 and E2. J Biol Chem. 1988 Oct 15;263 (29):14593-6
  • Kargman S, Wong E, Greig GM, Falgueyret JP, Cromlish W, Ethier D, Yergey JA, Riendeau D, Evans JF, Kennedy B, Tagari P, Francis DA, O'Neill GP. Mechanism of selective inhibition of human prostaglandin G/H synthase-1 and -2 in intact cells. Biochem Pharmacol. 1996 Oct 11;52 (7):1113-25
  • Kuno S, Ueno R, Hayaishi O, Nakashima H, Harada S, Yamamoto N. Prostaglandin E2, a seminal constituent, facilitates the replication of acquired immune deficiency syndrome virus in vitro. Proc Natl Acad Sci U S A. 1986 May;83 (10):3487-90
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