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Relaxin-2 Human E. coli

  • Regulatory status:RUO
  • Type:Recombinant protein
  • Source:E. coli
  • Other names:H2 relaxin, RLN2
  • Species:Human
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Cat. No. Size Price


RBG10286005 5 µg
RBG10286025 25 µg
RBG10286100 100 μg
PubMed Product Details
Technical Data

Type

Recombinant protein

Description

Relaxin-2 is a peptide hormone structurally related to insulin, which is expressed in the placenta, decidua, prostate, and ovaries during pregnancy. Of the three known relaxin genes, relaxin-2 is the only relaxin known to circulate in the blood. Relaxin-2 binds specifically to the LGR7 and LGR8 receptors, previously identified as “orphan” G protein-coupled receptors. Signaling by relaxin-2 through its target receptors enhances the growth of pubic ligaments, and the ripening of the cervix during birth. Recombinant Human Relaxin-2 is a non-glycosylated, 6.0 kDa, disulfide-linked, heterodimeric protein consisting of a 24 amino acid A-chain, and a 29 amino acid B-chain.

Source

E. coli

Purity

98%

Biological Activity

Data Not Available

Endotoxin

Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1–1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at-20°C to –80°C.

Storage/Expiration

 –20°C

Summary

Research topic

Diabetology - Insulin, C-Peptide, Proinsulin

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