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Manufactured by BioVendor

sCD22 Human Chinese Hamster Ovary Cells (CHO)

  • Regulatory status:RUO
  • Type:Recombinant protein
  • Source:Chinese Hamster Ovary Cells (CHO)
  • Species:Human
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Cat. No. Size Price

RBG10096005 5 µg
RBG10096020 20 µg
RBG10096100 100 μg
PubMed Product Details
Technical Data


Recombinant protein


CD22 is a B-lineage restricted 135 kDa glycoprotein whose cell surface expression is limited to resting and activated B lymphocytes. The physiological role of CD22 is still unknown. Targeted disruption of CD22 in mice results in a reduced level of surface IgM on peripheral B cells, suggesting a role for CD22 in limiting antigen receptor signaling. CD22 is a member of the Ig gene superfamily that uniquely binds a sialic acid-dependent ligand. Recombinant Human CD22 is a soluble 75.0 kDa protein which corresponds to the extracellular domain of CD22.

Amino Acid Sequence



Chinese Hamster Ovary Cells (CHO)



Biological Activity

Determined by its ability to inhibit the proliferation of Raji cells. The expected ED50 for this effect is 10–17 µg/ml.


Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).


Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1–1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at –20°C to –80°C




Research topic

Immune Response, Infection and Inflammation, Oncology

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