Select country change
Shopping cart (0 , 0,00 ) Menu Search
Manufactured by BioVendor

Tigar Human E. coli

  • Regulatory status:RUO
  • Type:Recombinant protein
  • Source:E. coli
  • Other names:TP53-induced glycolysis and apoptosis regulator (TIGAR)
  • Species:Human
Please select your region to see available products and prices.
Cat. No. Size Price

RBG10317005 5 µg
RBG10317025 25 µg
RBG10317100 100 μg
PubMed Product Details
Technical Data


Recombinant protein


TIGAR is a p53-inducible enzyme that catalyzes the hydrolysis of fructose-2–6 bisphosphate (F-2–6-BP) to fructose-6-phosphate and inorganic phosphate. F-2–6-BP is a powerful activator of 6-phosphofructose-1 kinase, the rate limiting enzyme of glycolysis. By lowering the intracellular level of F-2–6-BP, TIGAR expression leads to increased glucose processing via the pentose phosphate pathway, the major cellular source for NADPH. Recombinant Human TIGAR expressed in E. coli is a 29.9 kDa protein containing 269 amino acid residues.

Amino Acid Sequence



E. coli



Biological Activity

Data not available.


Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).


Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.5–1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at –20°C to –80°C.




Research topic

Apoptosis, Oncology

Related Products Docs