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References to Urinary Trypsin Inhibitor (UTI, bikunin, ulinastatin)

  • Balduyck M, Albani D, Jourdain M, Mizon C, Tournoys A, Drobecq H, Fourrier F, Mizon J. Inflammation-induced systemic proteolysis of inter-alpha-inhibitor in plasma from patients with sepsis. J Lab Clin Med. 2000 Feb;135 (2):188-98
  • Balduyck M, Mizon J. [Inter-alpha-trypsin inhibitor and its plasma and urine derivatives]. Ann Biol Clin (Paris). 1991;49 (5):273-81
  • Chawla RK, Lawson DH, Ahmad M, Travis J. Cancer-related urinary proteinase inhibitor, EDC1: a new method for its isolation and evidence for multiple forms. J Cell Biochem. 1992 Nov;50 (3):227-36
  • Chawla RK, Miller FW, Lawson DH, Nixon DW. Urinary cancer-related protein EDC1 and serum inter-alpha trypsin inhibitor in breast cancer. Tumour Biol. 1984;5 (6):351-63
  • Chirat F, Balduyck M, Mizon C, Laroui S, Sautiere P, Mizon J. A chondroitin-sulfate chain is located on serine-10 of the urinary trypsin inhibitor. Int J Biochem. 1991;23 (11):1201-3
  • DILLARD GH. The trypsin inhibitor of the urine in health and disease. J Lab Clin Med. 1950 Aug;36 (2):266-71
  • Endo S, Inada K, Yamashita H, Takakuwa T, Nakae H, Yamada Y, Kasai T, Taki K, Yoshida M. The inhibitory actions of protease inhibitors on the production of polymorphonuclear leukocyte elastase and interleukin 8. Res Commun Chem Pathol Pharmac. 1993 Oct;82 (1):27-34
  • Franck C, Pedersen JZ. Trypsin-inhibitory activities of acid-stable fragments of the inter-alpha-trypsin inhibitor in inflammatory and uraemic conditions. Scand J Clin Lab Invest. 1983 Apr;43 (2):151-5
  • Fries E, Blom AM. Bikunin--not just a plasma proteinase inhibitor. Int J Biochem Cell Biol. 2000 Feb;32 (2):125-37
  • Gebhard W, Hochstrasser K, Fritz H, Enghild JJ, Pizzo SV, Salvesen G. Structure of inter-alpha-inhibitor (inter-alpha-trypsin inhibitor) and pre-alpha-inhibitor: current state and proposition of a new terminology. Biol Chem Hoppe Seyler. 1990 May;371 Suppl:13-22
  • Hirose J, Ozawa T, Miura T, Isaji M, Nagao Y, Yamashiro K, Nii A, Kato K, Uemura A. Human neutrophil elastase degrades inter-alpha-trypsin inhibitor to liberate urinary trypsin inhibitor related proteins. Biol Pharm Bull. 1998 Jul;21 (7):651-6
  • Hochstrasser K, Feuth H, Fall J, Kemkes B. [Acidstable proteinaseinhibitors in blood plasma in different nepropathies (author's transl)]. Klin Wochenschr. 1974 Nov 1;52 (21):UNKNOWN
  • Hochstrasser K, Niebel J, Feuth H, Lempart K. [About degradation products of the inter-alpha-trypsin inhibitor in serum. I. The inter-alpha-trypsin inhibitor as precursor of the acid stable trypsin-plasmin-inhibitor of the serum (author's transl)]. Klin Wochenschr. 1977 Apr 1;55 (7):337-42
  • Hochstrasser K, Reisinger PW, Albrecht GJ, Wustrow TP. [Protease inhibitors as tumor-associated growth factors]. Laryngorhinootologie. 1989 Jan;68 (1):51-6
  • Inoue K, Takano H. Urinary trypsin inhibitor as a therapeutic option for endotoxin-related inflammatory disorders. Expert Opin Investig Drugs. 2010 Apr;19 (4):513-20
  • Jonsson-Berling BM, Ohlsson K, Rosengren M. Radioimmunological quantitation of the urinary trypsin inhibitor in normal blood and urine. Biol Chem Hoppe Seyler. 1989 Nov;370 (11):1157-61
  • Kobayashi H, Gotoh J, Terao T. Urinary trypsin inhibitor efficiently inhibits urokinase production in tumor necrosis factor-stimulated cells. Eur J Cell Biol. 1996 Dec;71 (4):380-6
  • Kobayashi H, Shinohara H, Takeuchi K, Itoh M, Fujie M, Saitoh M, Terao T. Inhibition of the soluble and the tumor cell receptor-bound plasmin by urinary trypsin inhibitor and subsequent effects on tumor cell invasion and metastasis. Cancer Res. 1994 Feb 1;54 (3):844-9
  • Kobayashi H, Suzuki M, Tanaka Y, Hirashima Y, Terao T. Suppression of urokinase expression and invasiveness by urinary trypsin inhibitor is mediated through inhibition of protein kinase C- and MEK/ERK/c-Jun-dependent signaling pathways. J Biol Chem. 2001 Jan 19;276 (3):2015-22
  • Kuwajima S, Matsui T, Kitahashi S, Kishida T, Noda T, Izumi Y, Naka K, Okuda K. Automated measurement of trypsin inhibitor