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Manufactured by BioVendor

VEGF-R1/FLT-1 Human HEK293

  • Regulatory status:RUO
  • Type:Recombinant protein
  • Source:HEK293
  • Other names:Vascular Endothelial Growth Factor Receptor 1, Fms-like tyrosine kinase 1, VEGFR-1, Fms-like tyrosine kinase 1, FLT-1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, FLT, Vascular permeability factor receptor, FLT1, FRT, VEGFR1
  • Species:Human
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Cat. No. Size Price

RD172420100 0.1 mg
PubMed Product Details
Technical Data


Recombinant protein


Total 675 AA. MW: 76.6 kDa (calculated). UniProtKB acc. No. P17948 (isoform 2, Ser27–His687). N-terminal linker (2 extra AA), C-terminal linker (2 extra AA) and C-terminal His-tag (10 extra AA).

Amino Acid Sequence





Purity as determined by densitometric image analysis: > 95 %


12 % SDS-PAGE separation of Human VEGFR-1 (HEK):
1. M.W. marker – 14, 21, 31, 45, 66, 97 kDa
2. Reduced and boiled sample, 2.5 μg/lane
3. Non-reduced and non-boiled sample, 2.5 μg/lane


< 0.1 EU/μg


Filtered (0.4 μm) and frozen from 0.3 – 0.7 mg/mL solution in phosphate buffer saline pH 7.4 containing 20% (w/v) glycerol.


Defrost at room temperature. Filter sterilize your culture media/working solutions containing this non-sterile product before using in cell culture.


Western blotting, ELISA, Cell culture and/or animal studies


On ice. Upon receipt, store the product at the temperature recommended below.


Store protein at –80°C. Protein remains stable until the expiry date when stored at –80°C. Avoid repeated freezing/thawing cycles.

Quality Control Test

BCA to determine quantity of the protein.

SDS PAGE to determine purity of the protein.

LAL to determine quantity of endotoxin.


This product is intended for research use only.


Research topic

Cytokines and chemokines and related molecules, Reproduction


VEGFR1, also known as FMS-related tyrosine kinase 1(FLT1). Oncogene FLT belongs to the src gene family and is related to oncogene ROS . Like other members of this family, it shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. FLT is mapped to 13q12. VEGF receptor 1 signaling is essential for osteoclast development and bone marrow formation in colony-stimulating factor 1-deficient mice. The standard product used in this kit is recombinant human VEGFR1, consisting of 905 amino acids with the molecular mass of 100KDa

Summary References (2)

References to VEGF-R1/FLT-1

  • Imbert A, Rosnet O, Marchetto S, Ollendorff V, Birnbaum D, Pebusque MJ. Characterization of a yeast artificial chromosome from human chromosome band 13q12 containing the FLT1 and FLT3 receptor-type tyrosine kinase genes. Cytogenet Cell Genet. 1994;67 (3):175-7
  • Niida S, Kondo T, Hiratsuka S, Hayashi S, Amizuka N, Noda T, Ikeda K, Shibuya M. VEGF receptor 1 signaling is essential for osteoclast development and bone marrow formation in colony-stimulating factor 1-deficient mice. Proc Natl Acad Sci U S A. 2005 Sep 27;102 (39):14016-21
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