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Apolipoprotein D (Apo D)

Human ApoD is a glycoprotein of 169 amino acids, which was discovered in plasma as an atypical lipoprotein. There, ApoD is peripherally associated with HDL via disulfide bond with ApoA-II , which itself forms an amphipathic a-helical belt that wraps around the lipid disc . ApoD was also isolated as a progesteronebinding protein abundant in mammary gross cystic disease fluid and it was found as a monomeric protein in apocrine secretion, where it seems to bind odorants. ApoD mRNA is expressed in a variety of organs as well as in certain human cancers. Indeed, ApoD has received attention as prognostic marker for various, often steroid-responsive tumors, including prostate cancer , breast carcinoma, and cutaneous malignant melanoma. In addition, ApoD is synthesized by astrocytes in the central nervous systém and there it seems to be involved in arachidonic acid transport, metabolism, and signaling. Notably, ApoD plays a well documented pathophysiological role in several psychiatric disorders , especially in schizophrenia.

1 result found in Immunoassays
2 results found in Proteins
2 results found in Antibodies

Immunoassays
Product Size Price
Apolipoprotein D Human ELISA

Type: Sandwich ELISA, Biotin-labelled antibody

RD193118200R 96 wells (1 kit)
 
Proteins
Product Size Price
Apolipoprotein D Human E. coli

Type: Recombinant

RD172118100 0.1 mg
 
Apolipoprotein D Human HEK293

Type: Recombinant

RD172118100-HEK 0.1 mg
 
Antibodies
Product Size Price
Apolipoprotein D Human, Rabbit Polyclonal Antibody

Type: Polyclonal Antibody

RD181118100 0.1 mg
 
Apolipoprotein D Human, Sheep Polyclonal Antibody

Type: Polyclonal Antibody

RD184118100 0.1 mg