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CCL27 (CTACK, CC chemokine ILC, Cutaneous T-cell-attracting chemokine, CTACK, Eskine, IL-11 R-alpha-locus chemokine, Skinkine, Small-inducible cytokine A27, C-C motif chemokine 27)

Cutaneous T-cell-attracting chemokine (CTACK)(CCL27) is a ligand for cell surface receptor CCR10. It is responsible for chemotaxis of skin-homing memory T cells during cutaneous inflammation. Interestingly, after CCR10-mediated internalization, CTACK, as well as a non-secreted splice variant of the same gene, can reach the nucleus and modulate transcription and cell behavior.

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