Type
 
											Sandwich ELISA, HRP-labelled antibody
												Applications
 
											Serum
												Sample Requirements
 
											25 µl/well
												Shipping
 
											At ambient temperature. Upon receipt, store the product at the temperature recommended below.
												Storage/Expiration
 
											Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).
															Calibration Curve
 
														
												Calibration Range
 
											2.5–500 IU/l
												Limit of Detection
 
											0.7 IU/l
												Spiking Recovery
 
											100,20%
												Dilution Linearity
 
											101,60%
								
							 
							
								
												Research topic
 
											Reproduction
												Summary
 
											Human Chorionic Gonadotropin (hCG) is a glycoprotein hormone normally produced by placenta during pregnancy. The hormone is present in blood and urine around seven to thirteen days following implantation of the fertilized ovum. Structurally intact hCG molecules consist of two non-covalently linked polypeptide subunits, the alpha and beta chain subunits. Measurement of intact hCG and of the alpha subunit of hCG appears to give similar results in blood and urine but not the levels of beta subunit. The measurement of free β-HCG in the first trimester of pregnancy has been reported as a useful marker in antenatal screening for Down Syndrome and other fetal aneuploidies. Increased free β-HCG values in combination with maternal age, the measurement of PAPP-A and the ultrasonic determination of nuchal translucency (NT) in pregnancy weeks 11 to 14 may detect up to 90 % of pregnancies with Down syndrom.
								
							 
							
	
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