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Human hsCRP ELISA

  • Regulatory status:RUO
  • Type:Sandwich ELISA, HRP-labelled antibody
  • Other names:C-Reactive Protein
  • Species:Human
Cat. No. Size Price


740011 96 wells (1 kit)
PubMed Product Details
Technical Data

Type

Sandwich ELISA, HRP-labelled antibody

Applications

Serum, Plasma

Sample Requirements

10 μl/well

Shipping

At ambient temperature. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Range

0–10 μg/ml

Limit of Detection

0.02 μg/ml

Note

The kits are CE-IVD certified and intended for professional use.

Summary

Features

  • European Union: for in vitro diagnostic use
  • Rest of the world: for research use only!

Research topic

Immune Response, Infection and Inflammation, Sepsis

Summary

CRP is an acute-phase protein, produced exclusively in the liver. Serum concentration of CRP increases significantly in cases of both infectious and noninfectious inflammation, of tissue damage and necrosis and in the presence of malignant tumours. CRP is present in the active stages of inflammatory disorders like rheumatoid arthritis, ankylosing spondylitis, Reiter’s syndrome, psoriatic arthropathy, systemic lupus erythematosus, polyarteritis, ulcerative colitis and Crohn’s disease. The CRP level increases dramatically following microbial infections, and this can be particularly helpful for the diagnosis and monitoring of bacterial septicemia in neonates and other immunocompromised patients at risk.

Product References (14)

References

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  • Khadir A, Kavalakatt S, Dehbi M, Alarouj M, Bennakhi A, Tiss A, Elkum N. DUSP1 Is a Potential Marker of Chronic Inflammation in Arabs with Cardiovascular Diseases. Dis Markers. 2018 Dec 13;2018:9529621. doi: 10.1155/2018/9529621. eCollection 2018. PubMed PMID: 30647800. PubMed CentralPMCID: PMC6311887. See more on PubMed
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  • Khadir A, Kavalakatt S, Madhu D, Hammad M, Devarajan S, Tuomilehto J, Tiss A. Fetuin-A levels are increased in the adipose tissue of diabetic obese humans but not in circulation. Lipids Health Dis. 2018 Dec 22;17(1):291. doi: 10.1186/s12944-018-0919-x. PubMed PMID: 30579336. PubMed CentralPMCID: PMC6303986. See more on PubMed
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Summary References (3)

References to CRP

  • Gewurz H, Mold C, Siegel J, Fiedel B. C-reactive protein and the acute phaseresponse. Adv Intern Med. 1982;27:345-72. Review. PubMed PMID: 7041546. See more on PubMed
  • Johnson HL, Chiou CC, Cho CT. Applications of acute phase reactants ininfectious diseases. J Microbiol Immunol Infect. 1999 Jun;32(2):73-82. Review.PubMed PMID: 11561579. See more on PubMed
  • Powell LJ. C-reactive protein--a review. Am J Med Technol. 1979Feb;45(2):138-42. Review. PubMed PMID: 106726. See more on PubMed
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