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IP-10 (Interferon-gamma inducible Protein 10kDa, CXCL10)

IP-10 (Interferon-gamma inducible Protein 10kDa) also known as CXCL10, is secreted by several cell types in response to IFNg and LPS. These cell types include monocytes, endothelial cells and fibroblasts.The gene for IP-10 is located on chromosome 4 in a cluster among several other cytokines and encodes a 98 amino acid precursor protein. IP-10 has been attributed to several roles, such as chemoattraction for monocytes and T cells (but not for neutrophils), inhibition of bone marrow colony formation and angiogenesis, promotion of T cells adhesion molecule expression. IP-10 shares a common receptor, CXCR3, with the chemokine MIG, but has been shown to play a distinct role in host defense in infections. IP-10 expression has been associated with HIV infection, is involved in inflammatory skin disease (6) and other allergic diseases; it appears in inflammation of the nervous system and in Alzheimer’s disease (astrocytes expressing IP-10 are commonly associated with senile plaques).

2 results found in Immunoassays
9 results found in Proteins
2 results found in Planar Arrays

Immunoassays
Product Size Price
IP-10 Human ELISA

Type: Sandwich ELISA, Biotin-labelled antibody

RGP019R 96 wells (1 kit)
 
IP-10 Mouse ELISA

Type: Sandwich ELISA, Biotin-labelled antibody

RAF077R 96 wells (1 kit)
 
Proteins
Product Size Price
IP-10 Human E. coli

Type: Recombinant

RBG10196005 5 µg
RBG10196025 25 µg
RBG10196100 100 μg
 
IP-10 Mouse E. coli

Type: Recombinant

RP1773360005 5 µg
RP1773360025 25 µg
RP1773361000 1 mg
 
IP-10 Rat E. coli

Type: Recombinant

RBG30062005 5 µg
RBG30062025 25 µg
RBG30062100 100 μg
 
Planar Arrays
Product Size Price
Q-Plex™ Human Chemokine (9-plex)

Type: Multiplex Assays

RQS120249HU 96 wells (1 kit)
 
Product Size Price
Q-Plex™ Human IP-10

Type: Singleplex Assays

RQS466849HU 96 wells (1 kit)