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Perforin has structural and functional similarities to complement component 9 (C9). Like C9, Perforin creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. It is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood.

No references to this molecule

1 results found in Immunoassays

Product: Size:

Perforin Human ELISA

Type: Sandwich ELISA, Biotin-labelled antibody

RGP021R 96 wells (1 kit)
Find more on Perforin on pubmed

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