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Resistin (Cysteine-rich secreted protein FIZZ3, Adipose tissue-specific secretory factor, ADSF, C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12-alpha-like 2, RETN, FIZZ3, HXCP1, RSTN, UNQ407/PRO1199)

Resistin, a product of the RSTN gene, is a peptide hormone belonging to the class of cysteine-rich secreted proteins which is termed the RELM family, and is also described as ADSF (Adipose Tissue-Specific Secretory Factor) and FIZZ3 (Found in Inflammatory Zone). Human resistin contains 108 amino acids as a prepeptide, and its hydrofobic signal peptide is cleaved before its secretion. Resistin circulates in human blood as a dimeric protein consisting of two 92 amino acid polypeptides, which are disulfide-linked via Cys26. Resistin may be an important link between obesity and insulin resistance. Mouse resistin, specifically produced and secreted by adipocyte, acts on skeletal muscle myocytes, hepatocytes and adipocytes themselves so that it reduces their sensitivity to insulin. Steppan et al. have suggested that resistin suppresses the ability of insulin to stimulace glucose uptake. They have also suggested that resistin is present at elevated levels in blood of obese mice, and is down regulated by fasting and antidiabetic drugs. Way et al., on the other hand, have found that resistin expression is severly suppressed in obesity and is stimulated by several antidiabetic drugs. Other studies have shown that mouse resistin increases during the differentiation of adipocytes, but it also seems to inhibit adipogenesis. In contrast, the human adipogenic differentiation is likely to be associated with a down regulation of resistin gene expression. Recent studies have shown that human resistin is expressed also in macrophages and may be a novel link between inflammation and insulin resistance.

3 results found in Immunoassays
7 results found in Proteins
3 results found in Antibodies
1 result found in Planar Arrays

Immunoassays
Product Size Price
Resistin Human ELISA

Type: Sandwich ELISA, Biotin-labelled antibody

RD191016100 96 wells (1 kit)
 
Resistin Mouse ELISA

Type: Sandwich ELISA, Biotin-labelled antibody

RD293016100R 96 wells (1 kit)
 
Resistin Rat ELISA

Type: Sandwich ELISA, Biotin-labelled antibody

RD391016200R 96 wells (1 kit)
 
Proteins
Product Size Price
Resistin Human E. coli

Type: Recombinant

RD172016300 0.1 mg
 
Resistin Human E. coli, Tag free

Type: Recombinant

RD172016301 0.1 mg
 
Resistin Mouse E. coli

Type: Recombinant

RD272016300 0.1 mg
 
Resistin Rat E. coli

Type: Recombinant

RBG30072005 5 µg
 
Resistin Rat E. coli

Type: Recombinant

RD372016300 0.1 mg
 
Resistin Rat E. coli

Type: Recombinant

RBG30072025 25 µg
RBG30072100 100 μg
 
Antibodies
Product Size Price
Resistin Human, Goat Polyclonal Antibody

Type: Polyclonal Antibody

RD184016220 0.1 mg
 
Resistin Human, Rabbit Polyclonal Antibody

Type: Polyclonal Antibody

RD181016220 0.1 mg
 
Resistin Rat, Rabbit Polyclonal Antibody

Type: Polyclonal Antibody

RD381016100 0.1 mg
 
Planar Arrays
Product Size Price
Q-Plex™ Human Resistin

Type: Singleplex Assays

RQS469149HU 96 wells (1 kit)