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Manufactured by BioVendor

sFas Ligand Human ELISA

  • Regulatory status:RUO
  • Type:Sandwich ELISA, Biotin-labelled antibody
  • Other names:CD178 antigen, CD95L protein
  • Species:Human
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Cat. No. Size Price


RAF100R 96 wells (1 kit)
PubMed Product Details
Technical Data

Type

Sandwich ELISA, Biotin-labelled antibody

Applications

Serum, Amniotic fluid, Plasma, Cell culture supernatant

Sample Requirements

50 µl/well

Storage/Expiration

Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Curve

Calibration Range

0.16–10.0 ng/mL

Limit of Detection

0.07 ng/ml

Intra-assay (Within-Run)

CV = 6.1%

Inter-assay (Run-to-Run)

CV = 7.0%

Spiking Recovery

85,00%

Dilutation Linearity

106,00%

Summary

Research topic

Apoptosis

Summary

Fas is a type I membrane protein that belongs to the TNF/nerve growth factor receptor family. Fas mediates apoptosis, the programmed cell death, when it is cross-linked with specific binding partners. FasL is predominantly expressed on activated T-cells and NK cells; thus FasL-mediated cell death is involved in the T or NK cell-mediated cytotoxicity, some pathologic tissue damages, and the regulation of lymphocyte homeostasis. Elevated expression levels of FasL have been measured in various proliferative disorders and cancers.

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