Cat # changed from REA212/96R to EA212/96
Type
Competitive ELISA, Immobilized antigen
Applications
Serum, Plasma-EDTA
Sample Requirements
20 µl patient serum or plasma
Shipping
At ambient temperature. Upon receipt, store the product at the temperature recommended below.
Storage/Expiration
Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).
Calibration Range
0.2 µmol/l – 3.0 µmol/l
Limit of Detection
0.03 μmol/l
Intra-assay (Within-Run)
4.9 – 5.4 %
Inter-assay (Run-to-Run)
4.3 – 9.6 %
Research topic
Blood pressure regulation and NO metabolism, Cardiovascular disease
Summary
The vascular endothelium plays a central role in the regulation of vascular structure and function, mainly due to the formation of endothelium-derived nitric oxide (NO). NO is formed by the enzyme NO synthetase (NOS) from the amino acid precursor L-arginine. NOS activity can be downregulated by ADMA, an endogenous inhibitor of NOS. Elevated ADMA levels in plasma have been found in clinical studies including patients with hypercholesterolemia, hypertension, chronic heart failure, chronic renal failure and other internal disorders. ADMA may have diagnostic relevance as a novel cardiovascular risk marker.
Instructions for Use (RUO)
Instructions for Use (RUO)
Safety Information (RUO)
MSDS (RUO)
Find documents for the lot
