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EndoTrap® HD 50

  • Regulatory status:RUO
  • Type:EndoTrap®HD
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Cat. No. Size Price


LET0012 50 mL settled resin
Product Details
Technical Data

Type

EndoTrap®HD

Description

EndoTrap® HD removes endotoxins (lipopolysaccharides/LPS) from aqueous solutions of a wide range of samples such as proteins, antibodies, vaccines, nucleic acids, buffers and cell extracts with excellent sample recovery rate. The EndoTrap® HD resin is especially designed to meet the needs of pharma and biotech industry for the efficient removal of endotoxins in biomanufacturing processes as well as any application that requires highest endotoxin removal rates.

EndoTrap® HD fulfils all requirements for industrial applications, and it can easily be integrated in/at early or late-stage purification processes. Moreover, High-Definition Matrix is also available for small-scale purification as pre-filled columns. EndoTrap® HD is manufactured by LIONEX GmbH in Germany.

Available Products:

EndoTrap® HD 1/1
Item no. LET0009 1 x 1 ml column, 25 mL 5x Equilibration Buffer, 25 mL 5x Regeneration Buffer, 25 mL 5x Storage Buffer

EndoTrap® HD 5/1
Item no. LET0010 5 x 1 ml column, 125 mL 5x Equilibration Buffer, 125 mL 5x Regeneration Buffer, 125 mL 5x Storage Buffer

EndoTrap® HD 5
Item no. LET0023 5 mL settled resin

EndoTrap® HD 10
Item no. LET0011 10 mL settled resin

EndoTrap® HD 50
Item no. LET0012 50 ml settled resin

EndoTrap® HD 250
Item no. LET0013 250 ml settled resin

EndoTrap® HD Buffer Kit
Item no. LET0031 125 mL 5x Equilibration Buffer, 125 mL 5x Regeneration Buffer, 125 mL 5x Storage Buffer

EndoTrap® HD Leakage ELISA
Item no. LET0014 96 determinations (12 x 8 well strip & frame)

Empty Columns Large
Item no. LET0019 pack of 5 columns

Empty Columns Small
Item no. LET0020 pack of 5 columns

Disposable Polypropylene Funnel
Item no. LET0018 pack of 5 funnels

Summary

Features

  • Best-in-class endotoxin binding capacity of > 5,000,000 EU/ml
  • Removes more than 99.99% of LPS
  • Excellent sample recovery rate >95%
  • Non-toxic bacteriophage-derived ligand, no cytotoxic effects
  • Re-use more than 10 times
  • pH sample range: 4-10
  • suitable for high salt conditions
  • suitable for e.g. TRIS, HEPES, MOPS or similar buffered samples
  • PBS buffer possible when enriched freshly with 0.1 mM calcium (magnesium) directly before use
  • EndoTrap® Leakage ELISA for ligand leakage monitoring
  • Available as resin (buffers on request).

Summary

EndoTrap® HD removes endotoxins (lipopolysaccharides/LPS) from aqueous solutions of a wide range of samples such as proteins, antibodies, vaccines, nucleic acids, buffers and cell extracts with excellent sample recovery rate.

The EndoTrap® HD resin is especially designed to meet the needs of pharma and biotech industry for the efficient removal of endotoxins in biomanufacturing processes as well as any application that requires highest endotoxin removal rates.

EndoTrap® HD fulfils all requirements for industrial applications, and it can easily be integrated in/at early or late-stage purification processes. Moreover, the High-Definition Matrix is also available for small-scale purification as pre-filled columns.

Endotoxin removal with EndoTrap® HD works effectively in the pH range of 4-9 and NaCl concentrations of 50-600 mM. Buffers such as HEPES, TRIS, MOPS, MES, and PIPES are recommended. Citrate buffers and chelators of divalent cations (like EDTA) have to be avoided

Product References (26)

References

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