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Human KIM-1 ELISA

  • Regulatory status:RUO
  • Type:Sandwich ELISA
  • Other names:Hepatitis A Virus Cellular Receptor 1, HAVcr-1, Kidney injury molecule 1, KIM-1, T-cell immunoglobulin and mucin domain-containing protein 1, TIMD-1, T-cell immunoglobulin mucin receptor 1, TIM, TIM-1, T-cell membrane protein 1, HAVCR1
  • Species:Human
Cat. No. Size Price


New RBL006R 96 wells (1 kit) $586,5
PubMed Product Details
Technical Data

Type

Sandwich ELISA

Applications

Serum, Urine

Sample Requirements

50 µl/well

Shipping

Shipped on blue ice packs. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

Store the complete kit at 2–8°C. Under these conditions, all components are stable until the expiration date (see label on the box).

Calibration Range

15.6 - 1000 pg/ml

Limit of Detection

7.8 pg/ml

Intra-assay (Within-Run)

n = 8
CV = 3.5%

Inter-assay (Run-to-Run)

n = 8
CV = 9.5%

Spiking Recovery

107.7%

Dilution Linearity

87.8%

Summary

Features

It is intended for research use only

The total assay time is less than 20 hours

The kit measures KIM-1

Assay format is 96 wells

Quality Controls are human serum based

Standard is a recombinant protein

Components of the kit are provided ready to use, concentrated or dried

Research topic

Renal disease

Summary

The urinary kidney injury molecule 1 (KIM-1) participates in renal tissue damage and repair and is proposed as a biomarker of early and subclinical AKI. KIM-1 is also elevated in the urine of a significant fraction of patients apparently recovered from an AKI. Besides its potential utility in the early and subclinical diagnosis of renal damage, this study suggests a new application of urinary KIM-1 in the non-invasive follow-up of renal repair after AKI.

Summary References (2)

References to KIM-1

  • Vaidya VS, Ford GM, Waikar SS, Wang Y, Clement MB, Ramirez V, Glaab WE, Troth SP, Sistare FD, Prozialeck WC, Edwards JR, Bobadilla NA, Mefferd SC, Bonventre JV. A rapid urine test for early detection of kidney injury. Kidney Int. 2009 Jul;76 (1):108-14
  • Vaidya VS, Ozer JS, Dieterle F, Collings FB, Ramirez V, Troth S, Muniappa N, Thudium D, Gerhold D, Holder DJ, Bobadilla NA, Marrer E, Perentes E, Cordier A, Vonderscher J, Maurer G, Goering PL, Sistare FD, Bonventre JV. Kidney injury molecule-1 outperforms traditional biomarkers of kidney injury in preclinical biomarker qualification studies. Nat Biotechnol. 2010 May;28 (5):478-85
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