Type
Sandwich ELISA
Applications
Serum
Sample Requirements
35 µl/well
Shipping
Shipped on blue ice packs. Upon receipt, store the product at the temperature recommended below.
Storage/Expiration
Store the complete kit at 2–8°C. Under these conditions, all components are stable until the expiration date (see label on the box).
Calibration Range
2000 - 20 pg/ml
Limit of Detection
4 pg/ml
Intra-assay (Within-Run)
CV =3,5%
Inter-assay (Run-to-Run)
CV =6,1%
Spiking Recovery
92%
Dilution Linearity
83%
Features
- It is intended for research use only
- The total assay time is less than 3 hours
- The kit measures specifically human TARC
- Assay format is 96 wells
- Standard is a recombinant protein
- Components of the kit are provided ready to use, concentrated or dried
Research topic
Autoimmunity, Oncology
Summary
TARC (thymus and activation-regulated chemokine), also known as C-C motif chemokine ligand 17 (CCL17), is expressed in the thymus and is produced by dendritic cells, endothelial cells, keratinocytes, and fibroblasts. TARC has affinity as a ligand for the C-C chemokine receptors CCR4 and CCR8 inducing Th2-dominant inflammatory reactions.
TARC has an important role in allergic diseases such as atopic dermatitis and bronchial asthma. High serum concentrations of TARC are observed in patients with atopic dermatitis, and its concentration reflects the disease activity. The concentration of TARC is also reported to be elevated in sputum of patients with bronchial asthma, and TARC may have potential as a therapeutic target. In clinical practice, TARC is useful also in selection of patients requiring new therapies of atopic dermatitis or asthma.
Find documents for the lot
Example Instructions for Use (RUO)
Example Instructions for Use (RUO)
