Secretory IgA is comprised of two immunoglobuline A molecules, which are joined by a J-protein and secretory component. The secretory component is synthesized by epithelial cells of the mucous membrane of gastrointestinal, respiratory and urogenitaltract. It is also produced by the saliva, tear and mammary glands. The determination of sIgA allows a first overview of the functionality of the gastrointestinal associated immune system.
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