BioVendor is introducing SophoMer™ F10: a synthetic polymer that improves the accuracy and reliability of diagnostic tests, replacing BSA in laboratories.
BioVendor is introducing SophoMer™ F10 as a precisely defined synthetic alternative to BSA, which, due to batch-to-batch variability and the risk of contamination, can interfere with sensitive assays. The polymer’s benefits are also confirmed by IVD-cleared CLIA assays, demonstrating its suitability for highly regulated diagnostic environments and its ability to better reduce non-specific signals.
At BioVendor, our mission has always been to redefine the standards of diagnostic laboratories by providing results you can truly rely on. As part of our commitment to continuous innovation, we are proud to announce the integration of SophoMer™ F10 into our processes—a move that sets a new benchmark for precision, reliability, and sustainability in the biotech industry.
Beyond the traditional: Why we are replacing BSA
For decades, Bovine Serum Albumin (BSA) has been the industry standard for blocking non-specific interactions in immunoassays. However, as an animal-derived product, BSA carries inherent limitations, including significant batch-to-batch variability and the risk of contamination with animal pathogens or enzymes like RNases and supply chain instability.
By adopting SophoMer™ F10, a next-generation, fully synthetic polymer reagent, BioVendor is moving beyond these traditional constraints to offer a superior alternative for life science and diagnostic applications.
From innovation to application: Benefits confirmed by our experts
At BioVendor, we don’t just adopt new technologies; we rigorously validate them to ensure they meet the highest diagnostic standards. Based on our internal implementation and extensive testing, we can now confirm several key performance advantages of SophoMer™ F10 over traditional Bovine Serum Albumin (BSA).
Here are the specific benefits we have verified through our experience:
- Reduced contamination risk: SophoMer™ F10 is a fully synthetic, animal-component-free formulation. This eliminates the risk of introducing pathogenic contaminants or animal immunoglobulins that can interfere with sensitive assays.
- Improved assay reliability: One of the greatest challenges in diagnostics is "noise" from non-specific protein binding. SophoMer™ F10 effectively suppresses these interactions more efficiently than BSA, even at significantly lower concentrations (often 5 to 10 times lower). This results in enhanced sensitivity and clearer results, particularly in complex matrices like blood proteins.
- Excellent long-term and thermal stability: it can be autoclaved SophoMer™ F10 demonstrates robust thermal stability and can be autoclaved without losing its functional properties. It remains stable in solution at room temperature for up to a week, providing a highly resilient and reliable component for long-term laboratory use.
- Unmatched consistency: Unlike BSA, which suffers from individual production batch variability, SophoMer™ F10 is a chemically defined material. This ensures precise batch-to-batch reproducibility, giving our clients total confidence in the long-term stability and performance of their assays.
- Enhanced Ethical & Environmental Standards: BioVendor is dedicated to sustainable CLIA solutions. Aligning with modern regulatory trends, SophoMer™ F10 provides an ethical, animal-free alternative that reduces our environmental footprint while maintaining peak analytical performance.
Proven innovation in every kit
The performance of SophoMer™ F10 is not just theoretical; it has already been demonstrated in IVD-cleared CLIA assays, underscoring its suitability for highly regulated diagnostic environments. Whether in ELISA, immunoblotting, or advanced biosensors, this polymer consistently outperforms traditional blockers by providing superior surface passivation and reducing non-specific signals.
BioVendor: your partner in innovation
By integrating SophoMer™ F10, BioVendor reinforces its position as a leader in biotechnology. We don’t just follow industry standards; we create them. This synergy between our established diagnostic expertise and cutting-edge polymer chemistry allows us to deliver a portfolio of kits that are faster, more accurate, and more reliable than ever before.
Join us in embracing the next generation of diagnostic excellence.
About Sophomer
Sophomer is a biotechnology company headquartered in Prague, Czech Republic, combining expertise in polymer chemistry and immunoassay optimization. Its SophoMer™ platform technology with the first polymer product, SophoMer™ F10, represents a new class of synthetic blockers that enable assay developers and manufacturers to reduce non-specific binding while improving consistency during both development and large-scale production.