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21-Hydroxylase (21-OH) Autoantibody ELISA

  • Regulatory status:RUO
  • Type:Sandwich ELISA, Biotin-labelled antibody
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Cat. No. Size Price


R21E/96R 96 wells (1 kit)
PubMed Product Details
Technical Data

Type

Sandwich ELISA, Biotin-labelled antibody

Applications

Serum

Sample Requirements

50 μl/well

Storage/Expiration

Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Summary

Research topic

Autoimmunity

Summary

Autoimmune destruction of the adrenal cortex is the most common cause of Addison’s disease and autoantibodies to the adrenal specific enzyme steroid 21-OH hydroxylase are important markers of adrenal autoimmunity. This can be the case if the disease presents as Addison’s disease or as part of the autoimmune polyglandular syndromes (APS) type I or type II.

References to Summary

References to 21-hydroxylase

  • Smith BR, Furmaniak J. Adrenal and gonadal autoimmune diseases. J Clin Endocrinol Metab. 1995 May;80 (5):1502-5
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