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Distributed product

Alpha-1-Antitrypsin in Stool Human ELISA

  • Regulatory status:RUO
  • Type:Sandwich ELISA, HRP-labelled antibody
  • Other names:α-1-AT, A1AT, A1-AT, A1A, AAT, alpha1-proteinase inhibitor, A1PI, alpha1-antiproteinase, A1AP, SERPINA1, SERPIN A1, serpin family A member 1, PI, PI1, PRO2275, alpha1AT, nNIF, serum trypsin inhibitor, STI
  • Species:Human
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Cat. No. Size Price


RIC6200 96 wells (1 kit)
PubMed Product Details
Technical Data

Type

Sandwich ELISA, HRP-labelled antibody

Applications

Serum, Plasma-EDTA, Stool

Sample Requirements

100 µl/well

Shipping

At ambient temperature. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Curve

Calibration Range

90-3,3 ng/ml

Limit of Detection

1.5 ng/ml

Intra-assay (Within-Run)

8,7%

Inter-assay (Run-to-Run)

11,9%

Spiking Recovery

80,3-105,2 %

Dilution Linearity

76,1-92,2 %

Summary

Features

  • European Union: for in vitro diagnostic use
  • Rest of the world: for research use only!

Research topic

Immune Response, Infection and Inflammation

Summary

Alpha-1-Antitrypsin is a 52 kD glycoprotein, which is produced by the liver, intestinal macrophages, monocytes and mucous membrane cells of the gut. It belongs to the group of acute phase proteins and is one of the most important proteinase inhibitor. Alpha-1-antitrypsin inhibits, beside others, the proteinases trypsin and the elastase of neutrophiles. A lack of α-1-AT leads to an enhanced proteolysis. Only a very small amount of alpha-1-antitrypsin is cleaved or resorbed in the gut. Therefore the measurement of α-1-AT in stool reflects the permeability of the gut during inflammatory processes.

Product References (11)

References

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