| Cat. No. | Size |
Price |
|
|---|---|---|---|
| New IC6400 | 96 wells (1 kit) | $635 |
Sandwich ELISA, HRP-labelled antibody
Stool
Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).
2.9 mU/g
89.72%
The linearity of the test ranges from 25 to 200 mU/g stool.
Diabetology - Autoimmunity
In the case of gluten intolerance, the body reacts hypersensitively to the gluten proteins (gliadin and glutenin) that are present in grain. 80-90% of patients have atypical or no symptoms and often do not know anything about their disease. In people with celiac disease, the intake of gluten leads to inflammation of the intestinal mucosa. The intestinal villi recede. Since the diseased intestinal mucosa can no longer absorb enough nutrients, a vitamin and mineral deficiency can occur. Hereditary factors (95% of patients have the HLA-DQ2 and HLA-DQ8 genes; up to 5% have the HLA-DR4 gene) play an important role in celiac disease, but the immune system and environmental factors also influence its development. Women get sick than men. According to the German Celiac Society, more recent screening tests show that the frequency of the disease is now between 1:100 and 1:200.
Antibodies against transglutaminase and/or gliadin can be detected in patients with gluten enteropathy. These antibodies can be detected regardless of whether the disease is manifest or silent or latent. In contrast to manifest gluten enteropathy, silent or latent forms do not show any atrophy of the villi of the small intestine, but pronounced intestinal or extraintestinal symptoms can still be present. The detection of anti-transglutaminase sIgA/IgA in the stool is suitable for screening and therapy monitoring. Elevated titers are not evidence of celiac disease (2). Celiac disease is detected by serum tests and a histological finding of villous atrophy.
Applications:
Example Instructions for Use (RUO)