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CardiNor Secretoneurin ELISA Assay

  • Regulatory status:RUO
  • Type:Sandwich ELISA, Biotin-labelled antibody
  • Other names:SN
  • Species:Human
This product is not available in United States!
Cat. No. Size Price


100-01 96 wells (1 kit)
PubMed Product Details
Technical Data

Type

Sandwich ELISA, Biotin-labelled antibody

Description

The CardiNor Secretoneurin ELISA Assay is an in vitro diagnostic test designed to detect and quantify the level of human secretoneurin (SN) in serum and plasma. It is indicated to be used in conjunction with clinical evaluation as an aid in assessing the prognosis of patients diagnosed with heart failure. The test is intended to be used by professionals.

Applications

Serum, Plasma-EDTA, Plasma-Heparin

Sample Requirements

10 µl/well

Shipping

On blue ice packs. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Range

10 - 250 pmol/l

Limit of Detection

5.1 pmol/l

Note

The kits are CE-IVD certified and intended for professional use.

Summary

Features

  • European Union: for in vitro diagnostic use
  • rest of the world: RUO
  • the kit measures secretoneurin in human serum and EDTA/ heparin plasma
  • Measuring range: 10 - 250 pmol/L
  • limit of detection 5.1 pmol/L

Research topic

Cardiovascular disease, Sepsis

Summary

Secretoneurin is a 33-amino acid neuropeptide produced by the endoproteolytic cleavage of chromogranin/secretogranin proteins. Secretoneurin is produced by neuroendocrine- and heart muscle cells and is detectable in the blood stream. Circulating secretoneurin concentrations are increased in patients with acute heart failure in proportion to disease severity in patients with arrhythmia-induced cardiac arrest2, after coronary artery bypass grafting3, and in critically ill patients with severe infections1 . Secretoneurin is a strong predictor of mortality in patients with acute heart failure, in acute respiratory failure patients with CVD, in patients with severe sepsis, and in patients with acute coronary syndrom.

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