Sandwich ELISA, HRP-labelled antibody
Serum, Plasma-EDTA, Plasma-Heparin
Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).
0 - 250 pmol/l
Limit of Detection
The kits are CE-IVD certified and intended for professional use.
European Union: for in vitro diagnostic use
Rest of the world: for research use only!
The total assay time is less than 2.5 hours
The kit measures secretoneurin in human serum and plasma (EDTA or heparin plasma are requested)
Assay format is 96 wells
Components of the kit are provided ready to use or concentrated
Cardiovascular disease, Sepsis
Secretoneurin is a 33-amino acid neuropeptide produced by the endoproteolytic cleavage of chromogranin/secretogranin proteins. Secretoneurin is produced by neuroendocrine- and heart muscle cells and is detectable in the blood stream. Circulating secretoneurin concentrations are increased in patients with acute heart failure in proportion to disease
severity in patients with arrhythmia-induced cardiac arrest2, after coronary artery bypass grafting3, and in critically ill patients with severe infections1
. Secretoneurin is a strong predictor of mortality in patients with acute heart failure, in acute respiratory failure patients with CVD, in patients with severe sepsis, and in patients with acute coronary syndrom.