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Distributed product

CH50

  • Regulatory status:RUO
  • Type:ELISA
  • Other names:Complement functionality
  • Species:Human
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Cat. No. Size Price


New DKO040 96 wells (1 kit)
PubMed Product Details
Technical Data

Type

ELISA

Applications

Serum

Sample Requirements

50 µl/well

Shipping

Shipped on ice packs. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

Store the complete kit at 2 – 8 °C. Under these conditions, all components are stable until the expiration date (see label on the box).

Calibration Range

CH50 value or % of reference calibrator

Summary

Features

European Union: for in vitro diagnostic use

Rest of the world: for research use only!

The total assay time is less than 2.5 hours

Quantitative determination of complement functionality in human serum

Assay format is 96 wells

Quality Controls (high and low) are ready to use

Reference calibartor is ready to use

For routine analysis

Research topic

Immune Response, Infection and Inflammation

Summary

The primary utility of the CH50 in the practice of an allergist-immunologist is to screen for complement- deficiency associated immunodeficiency (primarily classic or terminal complement component deficiencies). Absent or significantly reduced individual complement components may result in infections, Neisserial meningitis, or sepsis. A reduced CH50 in this situation warrants quantification and functional assays of individual complement components. Reduction of the CH50 occurs when individual complement component(s) are deficient or consumed.

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