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Distributed product

CIC C1q ELISA

  • Regulatory status:RUO
  • Type:ELISA
  • Other names:C1q-linked CIC, circulating immune complexes C1q
  • Species:Human
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Cat. No. Size Price


New DKO016 96 wells (1 kit)
PubMed Product Details
Technical Data

Type

ELISA

Applications

Serum, Plasma

Sample Requirements

10 µl/well

Shipping

Shipped on ice packs. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

Store the complete kit at 2 – 8 °C. Under these conditions, all components are stable until the expiration date (see label on the box).

Calibration Range

0 - 16 - 64 µgEq/mL

Limit of Detection

1 µgEq/mL

Intra-assay (Within-Run)

n=16
CV ≤ 5.3%

Inter-assay (Run-to-Run)

n=6
CV ≤ 6.0%

Spiking Recovery

94 - 106%

Summary

Features

European Union: for in vitro diagnostic use

Rest of the world: for research use only!

The total assay time is less than 1.5 hours

Quantitative determination of CIC C1q concentration in human serum or plasma

Assay format is 96 wells

Quality Controls (positive and negative) are ready to use

Standards are ready to use

For routine analysis

Research topic

Immune Response, Infection and Inflammation

Summary

C1q is involved in the classical complement pathway. The classical pathway is triggered by activation of the C1- complex (which consists of one molecule C1q and two molecules C1r and C1s), either by C1q's binding to antibodies from classes M and G, complexed with antigens, or by its binding C1q to the surface of the pathogen. The complement system might play a role in many diseases with an immune component, such as Barraquer-Simons Syndrome Alzheimer's disease, asthma, lupus erythematosus, various forms of arthritis, autoimmune heart disease and multiple sclerosis. Deficiencies of the terminal pathway predispose to both autoimmune disease and infections (particularly meningitis).

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