Type
ELISA
Applications
Serum, Plasma
Sample Requirements
10 µl/well
Shipping
Shipped on ice packs. Upon receipt, store the product at the temperature recommended below.
Storage/Expiration
Store the complete kit at 2–8°C. Under these conditions, all components are stable until the expiration date (see label on the box).
Calibration Range
0 - 16 - 64 µgEq/mL
Limit of Detection
1 µgEq/mL
Intra-assay (Within-Run)
n=16
CV ≤ 5.3%
Inter-assay (Run-to-Run)
n=6
CV ≤ 6.0%
Spiking Recovery
94 - 106%
Note
The kits are CE-IVD certified and intended for professional use.
Features
European Union: for in vitro diagnostic use
Rest of the world: for research use only!
The total assay time is less than 1.5 hours
Quantitative determination of CIC C1q concentration in human serum or
plasma
Assay format is 96 wells
Quality Controls (positive and negative) are ready to use
Standards are ready to use
For routine analysis
Research topic
Immune Response, Infection and Inflammation
Summary
C1q is involved in the classical complement pathway. The classical pathway is triggered by activation of the C1- complex (which consists of one molecule C1q and two molecules C1r and C1s), either by C1q's binding to antibodies from classes M and G, complexed with antigens, or by its binding C1q to the surface of the pathogen.
The complement system might play a role in many diseases with an immune component, such as Barraquer-Simons Syndrome Alzheimer's disease, asthma, lupus erythematosus, various forms of arthritis, autoimmune heart disease and multiple sclerosis. Deficiencies of the terminal pathway predispose to both autoimmune disease and infections (particularly meningitis).
Instructions for Use (RUO)
Instructions for Use (RUO)
Safety Information (RUO)
MSDS (RUO)
Product Brochure
CE IVD Assays
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