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  • Regulatory status:RUO
  • Type:Sandwich ELISA, HRP-labelled antibody
  • Other names:eosinophil derived neurotoxin
  • Species:Human
Cat. No. Size Price

Discount IC6500 96 wells (1 kit) $675
PubMed Product Details
Technical Data


Sandwich ELISA, HRP-labelled antibody




Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Limit of Detection

0.05 ng/ml

Intra-assay (Within-Run)

n = 10; CV = 6.8 %

Inter-assay (Run-to-Run)

n = 10; CV = 8.7 %

Spiking Recovery


Dilution Linearity




  • European Union: for in vitro diagnostic use
  • rest of the world: for research use only!
  • The kit is intended for the quantitative determination of EDN (eosinophil derived neurotoxin) in stool.
  • Assay format is 96 wells
  • Components of the kit are provided ready to use or concentrated

Research topic

Diabetology - Autoimmunity


After activation eosinophil granulocytes are segregating the cationic glycoprotein EDN (eosinophil derived neurotoxin). This 18-21 kDa single stranded glycosylated protein is also known as EPX (eosinophil protein X). Together with ECP (eosinophil cationic protein) EDN belongs to the ribonuclease superfamily. However EDN has a 100-fold increased ribonuclease activity. It is neurotoxic but not cytotoxic. The activation of eosinophil granulocytes is important during inflammatory processes in allergic reactions. Thus EDN is a marker for eosinophil activation and degranulation. The measurement of EDN in stool allows the detection of clinical or subclinical chronic inflammation in the gut. In patients with colitis ulcerosa and/or morbus crohn, the measurement of EDN gives information on the activity of the disease and the prediction of a relapse.


  • Differentiation of food allergy and food intolerance
  • Monitoring of an elimination diet
  • Inflammatory processes in the gut
  • Intestinal parasitosis

The ImmuChrom complete EDN kit allows an easy, rapid and precise quantitative determination of the eosinophil derived neurotoxin in biological samples. The kit includes all reagents ready to use for preparation of the samples.

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