Cat # changed from RSCYK140R to YK140
Type
Competitive ELISA, Immobilized antibody
Applications
Serum, Plasma-EDTA, Plasma-Heparin, Plasma-Citrate
Sample Requirements
25 µl/well
Shipping
At ambient temperature. Upon receipt, store the product at the temperature recommended below.
Storage/Expiration
Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).
Calibration Curve
Calibration Range
0.137–100 ng/ml
Intra-assay (Within-Run)
Plasma - CV (%) 3.1 - 7.2
Serum - CV (%) 3.5 - 8.9
Inter-assay (Run-to-Run)
Plasma - CV (%) 6.7 - 11.5
Serum - CV (%) 7.6 - 13.0
Spiking Recovery
Rat serum 111,2 %
Rat plasma 108,7 %
Research topic
Diabetology - Other Relevant Products, Animal studies
Summary
The proglucagon gene is expressed in both pancreatic A cell and intestinal L cell. Tissue-specific posttranslational processing of proglucagon by the prohormone convertase produced the different proglucagon derived peptides (PGDPs) in both pancreas and intestine. The most notable pancreatic PGDP is glucagon, whereas the L cell produces several structurally related peptides, including glucagon-like peptide 1 (GLP-1) and GLP-2, as well as glicentin and oxyntomodulin, which contain glucagon sequence in their molecules. Among PGDPs, GLP-2 has recently been found to show intestinal epithelial proliferation.
Instructions for Use (RUO)
Instructions for Use (RUO)
Safety Information (RUO)
MSDS (RUO)
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