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Distributed product

h-NSE ELISA

  • Regulatory status:RUO
  • Type:Sandwich ELISA
  • Other names:Gamma Enolase, 2-phospho-D-glycerate hydro-lyase, Enolase 2, Neural enolase, NSE, h-NSE
  • Species:Human
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Cat. No. Size Price


New DKO073 96 wells (1 kit)
PubMed Product Details
Technical Data

Type

Sandwich ELISA

Applications

Serum

Sample Requirements

25 µl/well

Shipping

Shipped on ice packs. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Range

0 - 4 - 20 - 50 - 100 ng/ml

Limit of Detection

0.19 ng/ml

Intra-assay (Within-Run)

n=16
CV≤ 4.4%

Inter-assay (Run-to-Run)

n=10
CV≤ 11.2%

Summary

Features

European Union: for in vitro diagnostic use

Rest of the world: for research use only!

The total assay time is less than 1.5 hours

Quantitative determination of neuron specific enolase concentration in human serum

Assay format is 96 wells

Calibrators are ready to use
Quality Controls (negative and positive) are ready to use

For routine analysis

Research topic

Neural tissue markers, Oncology

Summary

Neuron Specific Enolase (2-phospho-D-glycerate hydrolase) is an isoenzyme that belongs to the enolase family (homo- and heterodimer constituted of α, β and γ subunit) that is distingued from these by the presence of the specific γγ heterodimer. The clinical usefullness of hNSE like tumor marker is compared to non small cell lunge cancer (NSCLC), to neuroblastoma, to medullary carcinoma of the thyroid, pancreatic islet cell tumor and to non neoplastic condition of neuronal disease and cerebral trauma. hNSE ELISA test cannot be used as a screening test for neuroendocrine tumors, but may be used to follow levels in established diagnosis.

Product References (2)

References

  • Kumpaitiene B, Svagzdiene M, Drigotiene I, Sirvinskas E, Sepetiene R, Zakelis R, Benetis R. Correlation among decreased regional cerebral oxygen saturation,blood levels of brain injury biomarkers, and cognitive disorder. J Int Med Res.2018 Sep;46(9):3621-3629. doi: 10.1177/0300060518776545. Epub 2018 Jun 13. PubMedPMID: 29896989; PubMed Central PMCID: PMC6136023. See more on PubMed
  • Rothwell NJ, Stock MJ. Brown adipose tissue: does it play a role in thedevelopment of obesity? Diabetes Metab Rev. 1988 Sep;4(6):595-601. Review. PubMedPMID: 3065012. See more on PubMed
Summary References (1)

References to Neuron Specific Enolase

  • Karnak D, Beder S, Kayacan O, Ibis E, Oflaz G. Neuron-specific enolase and lung cancer. Am J Clin Oncol. 2005 Dec;28 (6):586-9
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