United States set
Menu Shopping cart $0 Search
Distributed product

IgG Rheumatoid Factor Mouse ELISA

  • Regulatory status:RUO
  • Type:Direct ELISA, HRP-labelled antibody
  • Other names:RF-IgG
  • Species:Mouse
Cat. No. Size Price

637-02679/633-02671 96 wells (1 kit) $865
PubMed Product Details
Technical Data

Cat # changed from 637-02679 to 633-02671


Direct ELISA, HRP-labelled antibody


Serum, Plasma-EDTA, Plasma-Citrate

Sample Requirements

1 µl/well


At ambient temperature. Upon receipt, store the product at the temperature recommended below.


Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Curve

Calibration Range

15.6–1 000 mU/ml

Limit of Detection

0.78 mU/ml


Research topic

Animal studies


Rheumatoid factors are autoantibodies against Fc region of of IgG and is found in 70-80% of patients suffering from chronic rheumatoid arthritis, and are considered to be closely related to its pathological syndrome. Experimental animal models with spontaneous autoimmune diseases similar to those in humans, and animals with artificially-induced inflammation have been used to elucidate the mechanism of autoimmune diseases and to search for potential new remedies. A representative model animal of spontaneous autoimmune diseases is MRL/lpr mouse. As MRL/lpr shows high incidence of lymph node tumor, nephritis, angitis, and arthritis, this animal strain is useful for studies of the mechanism of human autoimmune diseases including rheumatoid arthritis.
Autoantibodies found in MRL/lpr serum are IgG type rheumatoid factor, IgM type rheumatoid factor, anti-ssDNA antibodies, anti-dsDNA antibodies, and anti-Sm antibody, etc. This kit enables quantification and comparison of IgG type rheumatoid factor with a calibration curve using standard antibody preparation.

Product References (5)


  • Kumanogoh A, Shikina T, Watanabe C, Takegahara N, Suzuki K, Yamamoto M, Takamatsu H, Prasad DV, Mizui M, Toyofuku T, Tamura M, Watanabe D, Parnes JR, Kikutani H. Requirement for CD100-CD72 interactions in fine-tuning of B-cell antigen receptor signaling and homeostatic maintenance of the B-cell compartment. Int Immunol. 2005 Oct;17(10):1277-82. doi: 10.1093/intimm/dxh307. Epub 2005 Aug 19. PubMed PMID: 16113236. See more on PubMed
  • Oishi H, Mizuki S, Terada M, Kudo M, Araki K, Araki M, Nose M, Takahashi S. Increased expression of soluble form of vascular cell adhesion molecule-1 aggravates autoimmune arthritis in MRL-Fas(lpr) mice. Pathol Int. 2007 Nov;57(11):734-40. doi: 10.1111/j.1440-1827.2007.02165.x. PubMed PMID: 17922685. See more on PubMed
  • Yim YK, Lee H, Hong KE, Kim YI, Lee BR, Son CG, Kim JE. Electro-acupuncture at acupoint ST36 reduces inflammation and regulates immune activity in Collagen-Induced Arthritic Mice. Evid Based Complement Alternat Med. 2007 Mar;4(1):51-7. doi: 10.1093/ecam/nel054. Epub 2006 Aug 18. PubMed PMID: 17342241. PubMed CentralPMCID: PMC1810363. See more on PubMed
  • Takeda Y, Takeno M, Iwasaki M, Kobayashi H, Kirino Y, Ueda A, Nagahama K, Aoki I, Ishigatsubo Y. Chemical induction of HO-1 suppresses lupus nephritis by reducing local iNOS expression and synthesis of anti-dsDNA antibody. Clin Exp Immunol. 2004 Nov;138(2):237-44. doi: 10.1111/j.1365-2249.2004.02594.x. PubMed PMID: 15498032. PubMed CentralPMCID: PMC1809216. See more on PubMed
  • Ishihara K, Sawa S, Ikushima H, Hirota S, Atsumi T, Kamimura D, Park SJ, Murakami M, Kitamura Y, Iwakura Y, Hirano T. The point mutation of tyrosine 759 of the IL-6 family cytokine receptor gp130 synergizes with HTLV-1 pX in promoting rheumatoid arthritis-like arthritis. Int Immunol. 2004 Mar;16(3):455-65. doi: 10.1093/intimm/dxh045. PubMed PMID: 14978019. See more on PubMed
Related Products Docs