Cat # changed from RIC6100 to IC6100
Type
Sandwich ELISA, HRP-labelled antibody
Applications
Stool, Saliva
Sample Requirements
100 µl/well
Shipping
At ambient temperature. Upon receipt, store the product at the temperature recommended below.
Storage/Expiration
Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).
Calibration Range
600-22,2 ng/ml
Limit of Detection
3,1 ng/ml
Intra-assay (Within-Run)
5,4 %
Inter-assay (Run-to-Run)
6 %
Spiking Recovery
106,70%
Dilution Linearity
93,80%
Note
The kits are CE-IVD certified and intended for professional use.
Features
- European Union: for in vitro diagnostic use
- Rest of the world: for research use only!
Research topic
Autoimmunity, Immune Response, Infection and Inflammation
Summary
Secretory IgA is comprised of two immunglobuline A molecules, which are joined by a J-protein and a secretory component. The secretory component is synthesized by epithelial cells of the mucous membrane of gastrointestinal, respiratory and urogenitaltract. It is also produced by the saliva, tear and mammary glands. The plasma cells in the subendothelial area of mucous membranes are releasing a complex of two IgA-molecules, which are joined over the J-protein. This complex is binding to a secretory component, located at the surface of the epithel cell. After binding, the sIgA is transported across the cell and excreted by exocytosis. The determination of secretory IgA (sIgA) allows a first overview of the functionality of the gastrointestinal associated immune system (GALT). At this the secretory power and the degree of stimulation of the plasma cells of the intestinal submucosa is determined.
Instructions for Use (RUO)
Instructions for Use (RUO)
Safety Information (RUO)
MSDS (RUO)
Product Brochure
CE IVD Assays
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