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Manufactured by BioVendor

Interleukin-12/Interleukin-23 p40 Human ELISA

  • Regulatory status:RUO
  • Type:Sandwich ELISA, Biotin-labelled antibody
  • Other names:IL-12 subunit p40, Cytotoxic lymphocyte maturation factor 40 kDa subunit, NK cell stimulatory factor chain 2, IL-12B, IL-23, IL-23 subunit p40, T-cell stimulating factor
  • Species:Human
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Cat. No. Size Price


RAF034R 96 wells (1 kit)
PubMed Product Details
Technical Data

Type

Sandwich ELISA, Biotin-labelled antibody

Applications

Serum, Plasma, Cell culture supernatant

Sample Requirements

50 µl/well

Shipping

At ambient temperature. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Curve

Calibration Range

31.3–2000 pg/ml

Limit of Detection

< 10 pg/ml

Intra-assay (Within-Run)

CV = 4.7%

Inter-assay (Run-to-Run)

CV = 6.4%

Spiking Recovery

71,00%

Dilutation Linearity

109,80%

Summary

Research topic

Cytokines and chemokines and related molecules

Summary

IL-23 and IL-12 are heterodimeric cytokines which share the p40 subunit. Unlike IL-12, IL-23 has no effect on naive T cells but selectively activates memory T cells to secrete IFN-γ and IL-17. IL-23 is more potent than IL-12 in inducing long-lasting T-cell responses to viral antigens and can induce tumor-directed cytotoxic T-cell responses.

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