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Manufactured by BioVendor

Irisin ELISA

  • Regulatory status:RUO
  • Type:Competitive ELISA, Immobilized antigen
  • Other names:Fibronectin Type III Domain-containing Protein 5, Fibronectin Type III Repeat-containing Protein 2, FNDC5
  • Species:Human
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Cat. No. Size Price

RAG018R 96 wells (1 kit)
PubMed Product Details
Technical Data


Competitive ELISA, Immobilized antigen


Serum, Plasma, Cell culture supernatant


At ambient temperature. Upon receipt, store the product at the temperature recommended below.


Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Curve

Calibration Range

0.001–5 μg/ml

Limit of Detection

1 ng/ml


Research topic

Energy metabolism and body weight regulation


Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure. Circulating irisin levels were shown to be upregulated after acute exercise. Increase of irisin under conditions of obesity may indicate a physiological function to improve glucose tolerance.

Product References (17)


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  • Lavrova DP, Zavodovsky BV, Akhverdyan YR, Polyakova YV, Sivordova LE, Zborovskaya IA, Yakovlev AT. [Irisin as a new marker for the early diagnosis of low-traumatic fractures in rheumatoid arthritis.]. Klin Lab Diagn. 2018;63(11):702-706. doi: 10.18821/0869-2084-2018-63-11-702-706. PubMed PMID: 30776205. See more on PubMed
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