Select country set
Menu Shopping cart 0,00 Search
Manufactured by BioVendor

Periostin Human ELISA

  • Regulatory status:RUO
  • Type:Sandwich ELISA, HRP-labelled antibody
  • Other names:Periostin, PN, OSF-2, POSTN, Fasciclin-I like, Osteoblast Specific Factor 2 (Pleiotrophin, PTN, Heparin-binding growth-associated molecule, HB-GAM, Heparin-binding growth factor 8, HBGF-8, OSF-2, Heparin-binding neurite outgrowth-promoting factor 2, HBNF-2, Heparin-binding brain mitogen, HBBM ), NCK
  • Species:Human
Please select your region to see available products and prices.
Cat. No. Size Price

RAG019R 96 wells (1 kit)
PubMed Product Details
Technical Data


Sandwich ELISA, HRP-labelled antibody


Serum, Plasma, Cell culture supernatant


At ambient temperature. Upon receipt, store the product at the temperature recommended below.


Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Curve

Calibration Range

78–5000 pg/ml

Limit of Detection

15 pg/ml


Research topic

Bone and cartilage metabolism, Cardiovascular disease, Cytokines and chemokines and related molecules, Extracellular matrix, Oncology


Periostin was originally isolated as an osteoblast-specific factor that functions as a cell adhesion molecule for pre-osteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor β1 (TGF-β1) and bone morphogenetic protein 2 (BMP-2). Abnormal expression of periostin is also linked to angiogenesis and metastasis in epithelial tumors. Periostin up-regulation in cancers usually correlates with aggressiveness and/or poor survival.

Product References (4)


  • Novosad J, Krčmová I, Bartoš V, Drahošová M, Vaník P, Růžičková-Kirchnerová O, Teřl M, Krejsek J. Serum periostin levels in asthma patients in relation to omalizumab therapy and presence of chronic rhinosinusitis with nasal polyps. Postepy Dermatol Alergol. 2020 Apr;37(2):240-249. doi: 10.5114/ada.2020.94842. Epub 2020 May 6. PubMed PMID: 32489361. PubMed CentralPMCID: PMC7262810. See more on PubMed
  • He X, Bao Y, Shen Y, Wang E, Hong W, Ke S, Jin X. Longitudinal evaluation of serum periostin levels in patients after large-artery atherosclerotic stroke: A prospective observational study. Sci Rep. 2018 Aug 6;8(1):11729. doi: 10.1038/s41598-018-30121-5. PubMed PMID: 30082879. PubMed CentralPMCID: PMC6079094. See more on PubMed
  • Raman A, Reif GA, Dai Y, Khanna A, Li X, Astleford L, Parnell SC, Calvet JP, Wallace DP. Integrin-Linked Kinase Signaling Promotes Cyst Growth and Fibrosis in Polycystic Kidney Disease. J Am Soc Nephrol. 2017 Sep;28(9):2708-2719. doi: 10.1681/ASN.2016111235. Epub 2017 May 18. PubMed PMID: 28522687. PubMed CentralPMCID: PMC5576939. See more on PubMed
  • Liu Y, Li F, Gao F, Xing L, Qin P, Liang X, Zhang J, Qiao X, Lin L, Zhao Q, Du L. Periostin promotes the chemotherapy resistance to gemcitabine in pancreatic cancer. Tumour Biol. 2016 Nov;37(11):15283-15291. doi: 10.1007/s13277-016-5321-6. Epub 2016 Sep 30. PubMed PMID: 27696296. See more on PubMed
Summary References (3)

References to Osteoblast Specific Factor 2

  • Horiuchi K, Amizuka N, Takeshita S, Takamatsu H, Katsuura M, Ozawa H, Toyama Y, Bonewald LF, Kudo A. Identification and characterization of a novel protein, periostin, with restricted expression to periosteum and periodontal ligament and increased expression by transforming growth factor beta. J Bone Miner Res. 1999 Jul;14 (7):1239-49
  • Takeshita S, Kikuno R, Tezuka K, Amann E. Osteoblast-specific factor 2: cloning of a putative bone adhesion protein with homology with the insect protein fasciclin I. Biochem J. 1993 Aug 15;294 ( Pt 1):271-8
  • Ulstrup JC, Jeansson S, Wiker HG, Harboe M. Relationship of secretion pattern and MPB70 homology with osteoblast-specific factor 2 to osteitis following Mycobacterium bovis BCG vaccination. Infect Immun. 1995 Feb;63 (2):672-5
Related Products Docs