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Placental Lactogen Human ELISA

  • Regulatory status:RUO
  • Type:Sandwich ELISA, HRP-labelled antibody
  • Other names:PL
  • Species:Human
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Cat. No. Size Price


RIS0013R 96 wells (1 kit)
PubMed Product Details
Technical Data

Type

Sandwich ELISA, HRP-labelled antibody

Applications

Serum

Sample Requirements

10 µl/well

Shipping

At ambient temperature. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Curve

Calibration Range

1.25–20 mg/ml

Limit of Detection

0.3 mg/ml

Summary

Research topic

Reproduction

Summary

The physiological role of human placental lactogen (HPL) has not yet been established, but the great similarity to human growth hormone has stimulated the hypothesis about a function as a regulator of feto-placental growth and other physiological alterations during pregnancy. It has been suggested that the maternal serumlevel may reflect on “index of placental function”. Depressed levels of HPL are seen in association with intrauterine death, fetal distress in labor and birth asphyxia. This association is particularly strong if depressed levels are seen repeatedly, implying a chronic state of placental and therefore fetal compromise. Depressed levels are usually not present if the pregnancy has proceeded uneventfully to term. Elevated levels of HPL are usually indicative of optimal pregnancy outcome in singleton pregnancies. However, high levels may indicate substantial fetal pathology in specific diseases, namely diabetes mellitus and fetal macrosomia, rhesus isoimmunization and hydrops fetalis.

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