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Mouse/Rat Progesterone ELISA

  • Regulatory status:RUO
  • Type:Competitive ELISA
  • Species:Mouse, Rat
Cat. No. Size Price


RTC008R 96 wells (1 kit) $570,15
PubMed Product Details
Technical Data

Type

Competitive ELISA

Description

The BioVendor Mouse/Rat Progesterone ELISA is a competitive immunoassay for the quantitative measurement of progesterone in rat and mouse serum or plasma. For research use only. Not for use in diagnostic procedures.

Applications

Serum, Plasma

Sample Requirements

10 µl/well

Shipping

On blue ice packs. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Curve

Calibration Range

0.4–100 ng/ml

Limit of Detection

0.156 ng/ml

Summary

Features

  • RUO
  • calibration range 0.4-100 ng/ml
  • limit of detection 0.156 ng/ml

Research topic

Steroid hormones, Animal studies

Summary

Progesterone (4-pregnene-3, 20-dione) is a C21 steroid hormone containing a keto-group (at C-3) and a double bond between C-4 and C-5. Like other steroids, it is synthesized from cholesterol via a series of enzyme-mediated steps (1). Progesterone is a female sex hormone of primary importance in ovulation, fertility and menopause. It is particularly important in preparing the endometrium for the implantation of the blastocyte and in maintaining pregnancy (2). The rate of progesterone secretion may be affected by the degree of progestational activity of the uterus and the level of circulating LH (3). Analyses suggest that progesterone acts as an anti-glucocorticoid in rat adipose tissue in vivo, attenuating the glucocorticoid effect on adipose tissue metabolism (4). Furthermore it could be demonstrated that progesterone alone may be a valuable agent for management of postmenopausal osteoporosis (5). In female rodents, the determination of progesterone is a useful marker in evaluating and monitoring the state of the reproductive functions and pregnancy as well.

Product References (1)

References

  • Shaw S, Kumar U, Bhaumik G, Reddy MPK, Kumar B, Ghosh D. Alterations of estrous cycle, 3β hydroxysteroid dehydrogenase activity and progesterone synthesis in female rats after exposure to hypobaric hypoxia. Sci Rep. 2020 Feb 26;10(1):3458. doi: 10.1038/s41598-020-60201-4. PubMed PMID: 32103034. PubMed CentralPMCID: PMC7044287. See more on PubMed
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