SARS-CoV-2 S1 IgM ELISA Kit is a highly sensitive and specific immunoassay for qualitative detection of IgM class antibodies against the spike S1 subunit of SARS-CoV-2 in human blood.
Serum, Plasma, COVID-19
At ambient temperature. Upon receipt, store the product at the temperature recommended below.
The kit should be stored at 2-8°C, and all reagents should be equilibrated to room temperature before use. Immediately after use remaining reagents should be returned to cold storage (2-8°C). Once opened, the strips may be stored at 2-8°C for up to one month.
For Research Use Only. Not for diagnostic procedures.
The total assay time is less than 2.5 hours.
For the detection and qualitative measurement of IgM class antibodies against the spike protein S1 subunit of SARS-CoV-2 virus in human blood.
Includes human anti-S1 antibody positive control.
Assay format is 96 wells.
SARS-CoV-2 is an enveloped virus with a positive-sense RNA genome and a nucleocapsid of helical symmetry. The SARS-CoV-2 entry into host cells is mediated by the transmembrane spike (S) glycoprotein, which is the main target of neutralizing antibodies upon infection and the focus of the therapeutic and vaccine design. S comprises two functional subunits responsible for binding to the host cell receptor (S1 subunit) and fusion of the viral and cellular membranes (S2 subunit). The distal S1 subunit comprises the receptor-binding domain (RBD) and contributes to stabilization of the prefusion state of the membrane-anchored S2 subunit that contains the fusion machinery.
SARS-CoV-2 S1 IgM ELISA Kit is a highly sensitive and specific immunoassay for qualitative detection of IgM class antibodies against the S1 of SARS-CoV2 in human blood.