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Manufactured by BioVendor

TRAIL Human ELISA

  • Regulatory status:RUO
  • Type:Sandwich ELISA, Biotin-labelled antibody
  • Other names:TNF-related apoptosis-inducing ligand
  • Species:Human
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Cat. No. Size Price


RAF135R 96 wells (1 kit)
PubMed Product Details
Technical Data

Type

Sandwich ELISA, Biotin-labelled antibody

Applications

Serum, Plasma-EDTA, Plasma-Heparin, Plasma-Citrate, Cell culture supernatant

Sample Requirements

50 µl/well

Shipping

At ambient temperature. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Curve

Calibration Range

15.6–1000 pg/ml

Limit of Detection

5.0 pg/ml

Intra-assay (Within-Run)

CV = 6.5%

Inter-assay (Run-to-Run)

CV = 7.7%

Spiking Recovery

77,00%

Dilutation Linearity

102,80%

Summary

Research topic

Apoptosis, Oncology

Summary

TRAIL is a member of the TNF family which mediates cell death in a wide variety of malignant cell lines and primary tumor cells. It induces two different signals: cell death mediated by caspases and gene induction mediated by NFkappaB. TRAIL, which is ubiquitously expressed, exhibits very complex signalling and tumor-selective induction of apoptosis. TRAIL is involved in lymphatic neoplastic disorders and thyroid diseases and in the treatment of cancer like melanoma.

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