Competitive ELISA, Immobilized antigen
The Urine Pre-Clinical CartiLaps® (CTX-II) EIA detects degradation products of C-terminal telopeptides of type II collagen (CTX-II) in non-human urine and cell culture supernatant. The test is intended for research use only and not for use in diagnostic procedures.
Disruption of the structural integrity of cartilage is the major histological finding in osteoarthritis and rheumatoid arthritis. Type II collagen is the major organic constituent of cartilage. Fragments of type II collagen (CTX-II) are being released into circulation and subsequently secreted into urine following degradation of cartilage. In non-human urine, the CTX-II fragments can be quantified by Urine Pre-Clinical CartiLaps® EIA, which in addition is applicable for cell culture supernatants.
Urine, Cell culture supernatant
10 µL (Pre-diluted (1+3)
Store the complete kit at 2-8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).
Limit of Detection