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Vasoactive Intestinal Polypeptide ELISA

  • Regulatory status:RUO
  • Type:Competitive ELISA, Immobilized antibody
  • Other names:Vasoactive intestinal peptide, VIP, PHM27
  • Species:Human
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Cat. No. Size Price


New RCD033R 96 wells (1 kit)
PubMed Product Details
Technical Data

Type

Competitive ELISA, Immobilized antibody

Applications

Plasma-EDTA

Sample Requirements

75 µl/well

Shipping

On blue ice packs. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

Store the kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Range

25-800 pg/mL

Summary

Features

  • Research Use Only
  • The kit measures Vasoactive Intestinal Polypeptide in human serum-EDTA.
  • Assay format is 96 wells.

Research topic

Inflammatory bowel disease, Oncology, Pulmonary diseases

Summary

Vasoactive Intestinal Peptide (VIP) is a 28-amino acid neuropeptide belonging to the secretin/glucagon family of peptide hormones. It is primarily produced by neurons in the central and peripheral nervous systems, especially in the enteric nervous system, and by endocrine cells in the gastrointestinal tract, pancreas, and lungs. VIP plays a key role in regulating smooth muscle relaxation, secretion of water and electrolytes in the intestines, and modulation of immune responses. Clinically, VIP is an important biomarker for diagnosing rare neuroendocrine tumors called VIPomas, as elevated serum levels are highly specific and help identify the cause of severe secretory diarrhea (WDHA syndrome). Recent studies also highlight the potential of VIP as a marker in acute exacerbations of chronic obstructive pulmonary disease (COPD), and as a possible indicator of disease activity in inflammatory bowel disease, rheumatoid arthritis, or osteonecrosis.

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