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Human CGRP ELISA

  • Regulatory status:RUO
  • Type:Sandwich ELISA, AChE-labelled antibody
  • Species:Human
Cat. No. Size Price


RA19021R 96 wells (1 kit)
PubMed Product Details
Technical Data

Type

Sandwich ELISA, AChE-labelled antibody

Description

This Enzyme Immunometric Assay (EIA/ELISA) is based on a sandwich technique.

Applications

Serum, Cerebrospinal fluid, Plasma, Nervous tissue

Sample Requirements

100 µL/well

Shipping

On dry ice. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

Store the kit at -20°C

Calibration Range

7.8–1000 pg/ml

Limit of Detection

0.7 pg/mL (in EIA buffer) and 2 pg/mL (in plasma), calculated as the concentration of CGRP corresponding to the NSB average (n=8) plus three standard deviations.

Summary

Features

  • RUO
  • calibration range 7.8-1000 pg/ml

Research topic

Cardiovascular disease, Others

Summary

Calcitonin Gene Related Peptide (CGRP) is a potent vasodilator, and also elicits a number of other biological effects. Average plasma levels of CGRP have been reported to be from 0.8 pmol/L to 71 pmol/L (3 pg/mL to 269 pg/mL) in normal subjects. Increases in circulating CGRP levels have been noticed during hemodialysis, pregnancy, exacerbation of asthma and in cases of medullary thyroid carcinoma.

Summary References (1)

References to Calcitonin gene-related peptide

  • Frobert Y, Nevers MC, Amadesi S, Volland H, Brune P, Geppetti P, Grassi J, Creminon C. A sensitive sandwich enzyme immunoassay for calcitonin gene-related peptide (CGRP): characterization and application. Peptides. 1999;20 (2):275-84
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