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Rat CGRP ELISA

  • Regulatory status:RUO
  • Type:Sandwich ELISA, AChE-labelled antibody
  • Species:Rat
Cat. No. Size Price


RA19022R 96 wells (1 kit)
PubMed Product Details
Technical Data

Type

Sandwich ELISA, AChE-labelled antibody

Description

The enzymatic immunoassay (EIA/ELISA) is based on a sandwich technique.

Applications

Serum, Cerebrospinal fluid, Plasma, Nervous tissue

Sample Requirements

100 µl/well

Shipping

On dry ice. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

Store the kit at -20°C

Calibration Range

3.91–500 pg/ml

Limit of Detection

calculated as the concentration of CGRP corresponding to the NSB average (n = 8) plus three standard deviations, is: 0.7 (in Dilution Buffer) and 2 pg/mL (in plasma).

Summary

Features

  • RUO
  • calibration range 3.91-500 pg/ml

Research topic

Cardiovascular disease, Others, Animal studies

Summary

Calcitonin Gene Related Peptide (CGRP) is a potent vasodilator, and also elicits a number of other biological effects [4, 5]. Average plasma levels of CGRP have been reported to be from 0.8 pmol/L to 71 pmol/L (3 pg/mL to 269 pg/mL) in normal subjects. Increases in circulating CGRP levels have been noticed during hemodialysis, pregnancy, exacerbation of asthma and in cases of medullary thyroid carcinoma.

Summary References (1)

References to Calcitonin gene-related peptide

  • Frobert Y, Nevers MC, Amadesi S, Volland H, Brune P, Geppetti P, Grassi J, Creminon C. A sensitive sandwich enzyme immunoassay for calcitonin gene-related peptide (CGRP): characterization and application. Peptides. 1999;20 (2):275-84
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