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Deacylated Ghrelin ELISA

  • Regulatory status:RUO
  • Type:Sandwich ELISA
  • Other names:M46, Appetite-regulating hormone, Growth hormone secretagogue, Growth hormone-releasing peptide, Motilin-related peptide, Protein M46, GHRL, MTLRP, UNQ524/PRO1066
  • Species:Human, Mouse, Rat
Cat. No. Size Price

YK351 96 wells (1 kit) $770
PubMed Product Details
Technical Data


Sandwich ELISA



Sample Requirements



On blue ice packs. Upon receipt, store the product at the temperature recommended below.


Store all components of this kit at 2-8°C. This kit is stable under these conditions for 12 months from the date of manufacturing.

Calibration Range

13.6-870 fmol/mL

Limit of Detection

1.36 fmol/mL



Research Use Only.

This kit measures acylated ghrelin in plasma.

Assay format is 96 wells.

Components of the kit are provided ready-to-use, lyophilized , or concentrated.

Research topic

Diabetology - Other Relevant Products, Energy metabolism and body weight regulation


Ghrelin, a novel growth hormone releasing peptide is an acylated peptide that stimulates the release of growth hormone from pituitary. It was isolated from rat stomach and the structure was determined as a peptide consisting of 28-amino acid by Dr. Kenji kangawa (National Cardiovascular Center in Japan). The Ser3 residue of Ghrelin is modified by n-octanoic acid, a modification necessary for hormone activity. This Desacyl-Ghrelin ELISA kit measures only the Desacyl-Ghrelin based on the principle of 2 Site Sandwich enzyme-linked immunosorbent assay (ELISA). It can detect not only human Desacyl-Ghrelin but also rat/mouse Desacyl-Ghrelin (1-28). This kit is manufactured using the high specific antibody pairs generated by Dr. Kangawa and by following his protocol. (patent pending:PCT WO 01/07475 A1)

Product References (6)


  • Matsumoto M, Hosoda H, Kitajima Y, Morozumi N, Minamitake Y, Tanaka S, Matsuo H, Kojima M, Hayashi Y, Kangawa K. Structure-activity relationship of ghrelin: pharmacological study of ghrelin peptides. Biochem Biophys Res Commun. 2001 Sep 14;287(1):142-6. doi: 10.1006/bbrc.2001.5553. PubMed PMID: 11549267. See more on PubMed
  • Inui A. Ghrelin: an orexigenic and somatotrophic signal from the stomach. Nat Rev Neurosci. 2001 Aug;2(8):551-60. doi: 10.1038/35086018. PubMed PMID: 11483998. See more on PubMed
  • Gualillo O, Caminos J, Blanco M, Garcìa-Caballero T, Kojima M, Kangawa K, Dieguez C, Casanueva F. Ghrelin, a novel placental-derived hormone. Endocrinology. 2001 Feb;142(2):788-94. doi: 10.1210/endo.142.2.7987. PubMed PMID: 11159851. See more on PubMed
  • Hosoda H, Kojima M, Matsuo H, Kangawa K. Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue. Biochem Biophys Res Commun. 2000 Dec 29;279(3):909-13. doi: 10.1006/bbrc.2000.4039. PubMed PMID: 11162448. See more on PubMed
  • Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature. 1999 Dec 9;402(6762):656-60. doi: 10.1038/45230. PubMed PMID: 10604470. See more on PubMed
  • Date Y, Kojima M, Hosoda H, Sawaguchi A, Mondal MS, Suganuma T, Matsukura S, Kangawa K, Nakazato M. Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans. Endocrinology. 2000 Nov;141(11):4255-61. doi: 10.1210/endo.141.11.7757. PubMed PMID: 11089560. See more on PubMed
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