Shipped on ice packs. Upon receipt, store the product at the temperature recommended below.
Store the complete kit at 2 – 8 °C. Under these conditions, all components are stable until the expiration date (see label on the box).
0 - 0.1 - 0.4 - 1.0 - 4.0 - 10.0 µg/ml
Limit of Detection
94 - 111%
91 - 109%
European Union: for in vitro diagnostic use
Rest of the world: for research use only!
The total assay time is less than 1.5 hours
Quantitative determination of DHEA-S concentration in human serum or plasma
Assay format is 96 wells
Calibrators are ready to use
For routine analysis
Dehydroepiandrosterone sulfate (DHEA-S), is a natural steroid hormone found atop of the kidneys in the human body. DHEA-S derived from enzymatic conversion of DHEA in adrenal and extradrenal tissues. DHEA-S is also produced in the gonads, adipose tissue and the brain. It is the most abundant hormone in the human body and it is precursor of all sex steroids. As most DHEA-S is produced by the zona reticularis of the adrenal, it is argued that there is a role in the immune and stress response. DHEA-S may have more biologic roles. Its production in the brain suggests that is also has a role as a neurosteroid. Measurement of serum DHEA-S is a useful marker of adrenal androgen synthesis. Abnormally low levels may occur in have been reported in hypoadrenalism, while elevated levels occur in several conditions, e.g. virilizing adrenal adenoma and carcinoma, 21-hydroxylase and 3β-hydroxysteroid dehydrogenase deficiencies and in some cases of female hirsutism. Women with polycystic ovary syndrome tend to have normal or mildly elevated levels of DHEAS. As very little DHEA-S is produced by the gonads, measurement of DHEA-S levels may aid in the localization of androgen source in virilizing conditions.
DHEA-S levels show no diurnal variation.