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Manufactured by BioVendor


  • Regulatory status:RUO
  • Type:Sandwich ELISA
  • Other names:Matrix Metalloproteinase 3, Matrix metallopeptidase 3, MMP3
  • Species:Human
Cat. No. Size Price

New RBL003R 96 wells (1 kit) $655
PubMed Product Details
Technical Data


Sandwich ELISA


Serum, Plasma

Sample Requirements

10 µl/well


On blue ice packs. Upon receipt, store the product at the temperature recommended below.


Store the complete kit at 2–8°C. Under these conditions, all components are stable until the expiration date (see label on the box).

Calibration Range

0.2 - 10 ng/ml

Limit of Detection

0.05 ng/ml

Intra-assay (Within-Run)

n = 8
CV = 4%

Inter-assay (Run-to-Run)

n = 8
CV = 4%

Spiking Recovery


Dilution Linearity




It is intended for research use only

The total assay time is less than 3 hours

The kit measures total MMP-3

Assay format is 96 wells

Standard is a recombinant protein

Components of the kit are provided ready to use, concentrated or dried

Research topic

Bone and cartilage metabolism, Cardiovascular disease, Coronary artery disease, Oncology, Pulmonary diseases


Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases, responsible for the integrity of the basement membrane (BM) via degradation of extracellular matrix and BM components. MMPs are presented in various types of cells, including cardiomyocytes, cerebral neurons, hepatocytes, and many others, thus influencing various processes. MMP-3, also called stromelysin 1, is reported to be found in the cytosol of dopaminergic cells where its activation under stress conditions contributes to neuronal degradation. In chondrocytes, nuclear MMP-3 is suggested to be involved in the development of inflammatory arthritic diseases. Matrix metalloproteinase-3 (MMP-3) is implicated in the formation of atherosclerotic plaques, and the MMP-3 −1612 5A/6A polymorphism is associated with myocardial infarction (MI) and stable coronary artery disease (CAD).

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