IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute reaction phase, inflammation, bone metabolism, hematopoiesis, or cancer progression. It contributes to chronic inflammation in obesity, insulin resistance, inflammatory bowel disease, arthritis, sepsis, and atherosclerosis. BioVendor's rat IL-6 sandwich ELISA kit is an immunoassay using biotin-labeled antibody and streptavidin-HRP for measurement in serum and cell culture supernatants.