Type
Sandwich ELISA, HRP-labelled antibody
Applications
Serum, Plasma, Cell culture supernatant, COVID-19
Sample Requirements
50 µl/well
Shipping
At ambient temperature. Upon receipt, store the product at the temperature recommended below.
Storage/Expiration
Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).
Calibration Curve
Calibration Range
0.31–20 ng/ml
Limit of Detection
0.27 ng/ml
Intra-assay (Within-Run)
CV = 7.2%
Inter-assay (Run-to-Run)
CV = 9.8%
Spiking Recovery
75.0 %
Dilution Linearity
86,40%
Research topic
Cytokines and chemokines and related molecules, Oncology, COVID-19
Summary
The receptor of the cytokine IL-2 plays a crucial role in the regulation of the immune response. Binding of IL-2 to its receptor (IL-2R) on the surface of T-lymphocytes triggers a series of intracellular signaling events that result in the activation and proliferation of resting T cells and in the generation of helper, suppressor and cytotoxic T cells, which mediate immune reactions. sIL-2R is a marker for T cell activation. It can be an indicator of a wide spectrum of disorders involving immune activation. IL2R can be found at significantly elevated levels in a broad range of disorders such as tumor diseases, autoimmune diseases (e.g. sarcoidosis), organ rejection and various infections.
Instructions for Use (RUO)
Instructions for Use (RUO)
Safety Information (RUO)
MSDS (RUO)
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