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Manufactured by BioVendor

sInterleukin-2 Receptor Human ELISA

  • Regulatory status:RUO
  • Type:Sandwich ELISA, HRP-labelled antibody
  • Other names:IL-2R, Interleukin-2 receptor alpha, CD25 antigen
  • Species:Human
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Cat. No. Size Price


RAF106R 96 wells (1 kit)
PubMed Product Details
Technical Data

Type

Sandwich ELISA, HRP-labelled antibody

Applications

Serum, Plasma, Cell culture supernatant

Sample Requirements

50 µl/well

Shipping

At ambient temperature. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Curve

Calibration Range

0.31–20 ng/ml

Limit of Detection

0.27 ng/ml

Intra-assay (Within-Run)

CV = 7.2%

Inter-assay (Run-to-Run)

CV = 9.8%

Spiking Recovery

75.0 %

Dilutation Linearity

86,40%

Summary

Research topic

Cytokines and chemokines and related molecules, Oncology

Summary

The receptor of the cytokine IL-2 plays a crucial role in the regulation of the immune response. Binding of IL-2 to its receptor (IL-2R) on the surface of T-lymphocytes triggers a series of intracellular signaling events that result in the activation and proliferation of resting T cells and in the generation of helper, suppressor and cytotoxic T cells, which mediate immune reactions. sIL-2R is a marker for T cell activation. It can be an indicator of a wide spectrum of disorders involving immune activation. IL2R can be found at significantly elevated levels in a broad range of disorders such as tumor diseases, autoimmune diseases (e.g. sarcoidosis), organ rejection and various infections.

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